Objective :: Education :: Work Experience :: Research Summary :: Skills and Achievements :: Publications :: Personal Interests :: References

Objective

To participate in research and development in bioinformatics to further the advancement of the field and add meaningfully to the body of human knowledge.

Education

2010 - present   University of Wisconsin — MadisonMadison, WI
Ph.D. — Computer Sciences

• Research Assistant: Alternative RNA Splicing
• Artificial Intelligence: Computer Science 731, 760
• Biostatistics: Statistics 541
• Biochemistry: Genetics 466, Chemistry 341, Biochemistry 501

2007 - 2009   University of Wisconsin — MadisonMadison, WI
Masters — Computer Sciences

• CIBM Predoctoral Fellow (three year award)
• Research Project: Visualization of Dose Shaping for Cancer Treatment
• Bioinformatics: Computer Science 576, 776
• Artificial Intelligence: Computer Science 540

2005 - 2007   University of Wisconsin — MadisonMadison, WI
Bachelor of Arts — Mathematics
Certificate — Computer Sciences

• Honors in the Major — Mathematics
• Research: Math 561, 681-682 Honors Thesis
• Analysis: Math 521-522, 551-552, 567
• Optimization: Computer Science 525, 635

Work Experience

2010 - present   UW Computer Sciences DepartmentMadison, WI
Research Assistant

• Development of open-source software for generating alternative RNA splice graphs based on RNA-Seq data
• Article in pre-publication: Inference of alternative splicing from RNA-Seq data with probabilistic splice graphs

2009 - 2010   Capital OneRichmond, VA
Systems Analyst I

• Research and analysis of backend systems and internal tools for online banking site
• Data analysis for problem mitigation on Bank and Credit Card websites
• Design and initial development of internal tool for website testing

2008 - 2009   UW Computer Sciences DepartmentMadison, WI
Teaching Assistant/Instructor

• Development of lesson plans and syllabus in association with other instructors
• Development of handouts (e.g. 1,2) for lecture enhancement
• In-class instruction as sole lecturer

2007 - 2008   Computation and Informatics in Biology and MedicineMadison, WI
Research Fellow

• Research into methods of optimization of radiotherapy treatment
• Implementation of optimization models in GAMS
• Development of visualization tools using C++, FLTK
• Funded by a grant from the National Institutes of Health

2006 - 2007   Mitchell LabMadison, WI
Software/Web Developer

• Design of geometric constructs for improving analysis program
• Implementation in C
• Additional front-end web application development

2006       Computation and Informatics in Biology and MedicineMadison, WI
Undergraduate Trainee

• Cross-disciplinary training in biological sciences
• Text mining research
• Front-end web application development - FADE server
• Funded by a grant from the National Institutes of Health

Research Summary

Currently I am assisting in the Dewey Lab's research on alternative splice graphs for RNA gene transcription. I will be implementing versions of their open source software for splice graph generation and analysis, with aims to assist in stem cell differentiation research and cancer therapy.

My Master's research in treatment planning methods for radiotherapy for cancer patients compared various linear and nonlinear methods for their effectiveness, speed, and accuracy. I additionally developed an interactive tool for visualization of treatment plans.

Publications

• S. Darnell, L. LeGault, and J. Mitchell. KFC Server: interactive forecasting of protein interaction hot spots.
  Nucleic Acids Research 2008 36(Web Server issue): W265-W269
• L. LeGault. An interactive GUI tool for radiotherapy treatment planning. Master's Thesis 2009.
• L. LeGault. A statistical analysis of the traditions of the Super Bowl MVP award. 15 Feb 2011.
• L. LeGault and C. Dewey. Inference of alternative splicing from RNA-Seq data with probabilistic splice graphs. Pre-publication.

Skills and Achievements

• Computational and analytic mathematics — high intermediate
• LaTeX — intermediate, self-taught
• Java 1.5-1.6, C++, C — intermediate, self- and formally-taught
• Python — beginner, self-taught
• FLTK (Fast Light ToolKit) — intermediate, self-taught
• Matlab — low intermediate, self-taught
• GAMS — low intermediate
• HTML, CSS, XHTML — intermediate, self-taught
• PHP, MySQL — intermediate, self-taught
• Spoken languages: Spanish (intermediate), French (intermediate), Mandarin (beginner)
• Adobe InDesign, Photoshop — intermediate

OS Proficiency:

• Mac OS X — low advanced
• Linux/Unix — intermediate
• Windows XP — low intermediate

CIBM Predoctoral Fellow (three year award); Irma L. Newman Scholar; National Merit Scholar; National Honor Society; Howard Coughlin Memorial Scholar; Bausch & Lomb Science Award winner; Undergraduate Research Symposium 2006-07

Personal Interests

Badger Herald comic artist (daily), piano, classical voice, swimming, cycling, dance (modern and ballet), yoga, stage managing (theatre and dance), Incident Response Team dispatcher for various Midwestern Anime conventions, occasional Wikipedia editing, web design

References

References and letters of recommendation available on request.

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