Uses of Protein Motion
Van Wynsberghe, Adam W., and Qiang Cui. Interpreting Correlated Motions Using Normal Mode Analysis
- Identify flexible and rigid motifs in large biomolecules, which may suggest sites for mutation or other experiments.
- Refine structural data
- Search for ligand binding sites
Ma, Jianpeng. Usefulness and Limitations of Normal Mode Analysis in Modeling Dynamics of Biomolecular Complexes
- Structural refinement against x-ray diffraction data, electron cryomicroscopy and fiber diffraction