Statistical Genomics Course (Stat 692)
Spring 2001
Brian S. Yandell (yandell@stat.wisc.edu)
www.stat.wisc.edu/~yandell/statgen/course/

NOTE: Current plan is to offer this course again in Spring 2003. Depending on other offerings (perhaps a microarray course), I may focus only on QTL. I will use a text that is being written joingly with Zhao-Bang Zeng, Gary Churchill, and Karl Broman. More later. NOTE: Time is being changed from 9:30-10:45 to 11-12:15 tue/thu to accomodate some time conflicts.


Credits

The course is officially listed as 1-3 credits. Three credits goes along with doing projects and homework for the entire course. 1-2 credits is appropriate for students who are either only interested in part of the course (e.g. only in microarrays or only in QTLs); they will be expected to complete the full work for that module. As with any advanced topic, you will only learn the material by actually doing the work!

Interested students can register directly for Stat 692. Auditors are encouraged to be "official" to gain computer access to our system and software used during the course. I would appreciate an email to yandell@stat.wisc.edu to anticipate class size. Please indicate (briefly) your statistical and biological background, in terms of courses, degrees or practical experience. Developing information about this course and other material related to Statistical Genomics may be found at www.stat.wisc.edu/~yandell/statgen/course.


Objective

The objective of this course is to familiarize students with state-of-the-art statistical methods for analyzing experiments involving genomic data in the form of (a) molecular markers, genetic linkage maps and complex phenotypic (quantitative) traits and/or (b) gene expression microarray data across multiple conditions. Construction and use of genetic linkage maps to infer quantitative trait loci (QTL) will be covered. Issues involving whole-genome analysis will be highlighted.

Prerequisites

Biology students should have a year sequence in statistical methods (Stat/For/Hort 571-572 or equivalent) and a readiness to learn. Statistics students should have an appreciation for data analysis in biology. A general introduction to concepts of Mendelian inheritance is assumed (Genetics 466 or equivalent).

Course Scheduling

   Credits        1-3
   Class Number   Stat 692
   Class Hours    11-12:15 tue/thu 1207 CompSci&Stat Center
   World Wide Web http://www.stat.wisc.edu/~yandell/statgen/course/

   Instructor     Brian Yandell, 4367 CSSC, 262-1157
                  yandell@stat.wisc.edu

Related Courses & Seminars

Courses and seminars listed below are on related topics, either from a biological, mathematical or computational perspective. I am attempting to coordinate among instructors/organizers with the aim to have reciprocal lectures as appropriate. Note dates and titles of my talks in other these courses or seminars. I expect other instructors to reciprocate, to build linkages.

Other Links and Information

Return to Statistical Genomics Page.
www.stat.wisc.edu/~yandell/statgen/course/ by Brian Yandell (yandell@stat.wisc.edu)