life science food and beverage environmental protection forensic founded 1998 headquarters bratislava slovakia area served global key people robert mistrik ceo and chief science officer juraj lutisan chief software architect milos suchy chief data officer products mass frontier mzcloud number of employees 13 website http www.highchem.com highchem is a scientific software company based in bratislava slovakia which focuses on developing mass spectrometry software and cloud solutions for data processing and the identification of compounds . in addition to software and cloud solutions highchem builds curated data collections of experimental mass spectra fragmentation patterns quantum chemically calculated fragments and organism specific biochemical data . its products are used by over 2 000 customers in pharmaceutical biomarker forensic environmental protection food control and related applications . highchem is affiliated with thermo fisher scientific . contents 1 history 2 products 3 see also 4 references history edit in 1998 highchem released mass frontier a software for interpretation of mass spectra . in 2003 the company developed fragmentation library a collection of literature based fragmentation mechanisms . in 2004 highchem implemented high resolution capable mass spectrometry database technology . in 2004 precursor ion fingerprinting method was invented . 1 from 2008 to 2011 highchem was a partner in the metacancer consortium 2 a collaborative project for the identification and validation of a new breast cancer biomarker . 3 in 2009 highchem introduced fragment ion search fish 4 a method for metabolite identification from lc ms data . in 2011 the company implemented a third generation spectra correlation algorithm into mass frontier software . since 2012 highchem has been an associated partner in the marie curie actions fp7 itn project eda emerge . 5 in 2013 mzcloud 6 went online . in 2014 highchem became a full member of norman 7 a network of reference laboratories research centers and related organizations for monitoring emerging environmental substances air pollution soil pollution water pollution . in 2015 highchem launched a fragment annotation project of more than 2 million ions using quantum chemical methods . products edit highchem mass frontier is a software package for the management evaluation and interpretation of mass spectral and chromatographic data . it provides fragment prediction methods relying on empirical fragmentation rules and a fragmentation library of more than 100 000 individual unimolecular ion decomposition reaction mechanism extracted from peer reviewed literature . 8 mzcloud is a web based mass spectral database that comprises a curated collection of high and low resolution tandem mass spectra acquired under a number of experimental conditions which address the problem of spectra reproducibility . spectra are filtered manually recalibrated and annotated by fragments processed by quantum chemical methods . data are freely searchable by spectrum spectral tree sub structure fragment precursor ion mass to charge ratio monoisotopic mass and chemical name . in addition to the spectral and structural data mzcloud also includes break down curves . see also edit list of mass spectrometry software list of chromatography software metabolomics computational chemistry drug development drug discovery references edit sheldon michelle t. ; mistrik robert ; croley timothy r. 2009 . determination of ion structures in structurally related compounds using precursor ion fingerprinting . journal of the american society for mass spectrometry . 20 3 370 376 . doi 10.1016 j.jasms .2008.10.017 . pmid 19041260 . metacancer identification and validation of new breast cancer biomarkers based on integrated metabolomics . genetic engineering & biotechnology news metabolite profiling speeds diagnostic efforts . new fragment ion search fish function . eda emerge . mzcloud a tandem mass spectral database . norman network . press release mass frontier 7.0 . retrieved from https en.wikipedia.org w index.php title highchem & oldid 723046200 categories 1998 establishments in slovakiacompanies based in bratislavamass spectrometry softwaresoftware companies established in 1998software companies of slovakia navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 31 may 2016 at 17 33 . text is available under the creative commons attribution sharealike license ; 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