please help improve it or discuss these issues on the talk page . learn how and when to remove these template messages this article contains content that is written like an advertisement . please help improve it by removing promotional content and inappropriate external links and by adding encyclopedic content written from a neutral point of view . february 2014 learn how and when to remove this template message this article relies too much on references to primary sources . please improve this by adding secondary or tertiary sources . february 2014 learn how and when to remove this template message this article is an orphan as no other articles link to it . please introduce links to this page from related articles ; try the find link tool for suggestions . february 2014 learn how and when to remove this template message isochem type s.a.s industry chemicals and speciality products founded 1974 headquarters vert le petit france key people bj rn schlosser ceo products chemicals number of employees 330 2016 website www.isochem.eu isochem is a french chemicals company specialized in custom synthesis . the company s products and services are primarily destined for the following market sectors pharmaceuticals apis or active ingredients for medicinal products and intermediates cosmetics specialty chemicals . the company operates from four production sites in france and also has one industrial subsidiary outside france wychem in the uk . contents 1 history 2 industrial sites and specific expertise 3 references 4 external links history edit 1974 isochem created in gennevilliers 1977 pithiviers ex . agrifarm site opened 1979 1st u.s. food and drug administration fda audit and approval ; export market development 1990 isochem joins groupe snpe 1991 isochem acquires the vert le petit site ex ircha fine chemicals and propeptide 1 2003 acquisition of the pont de claix platform and the hungarian subsidiary framochem 2010 acquisition of isochem by the german industrial holding company aurelius ag 2 2012 acquisition of wychem uk by isochem 3 4 2014 sale of framochem subsidiary by isochem initially specialized in the extraction and hemisynthesis of natural substances such as quinine isochem has gradually expanded its expertise in the field of multi step industrial production 5 encompassing a variety of operations including grignard friedel crafts sandmeyer vilsmeier haack reaction deprotonation using butyllithium reduction using metal hydrides and hydrogenation . 6 in the 1990s synergies with groupe snpe enabled isochem to implement new technologies such as phosgenation 7 nitration and manufacture of amino acid derivatives such as ncas 8 9 uncas and peptides . 10 11 industrial sites and specific expertise edit four sites in france vert le petit head office and production phosgene chemistry gennevilliers fractionned distillation cold reactions 70 c pithiviers hydrogenation under pressure waste processing 12 13 pont de claix active ingredients and intermediates for agrochemicals . one industrial subsidiary outside france wychem united kingdom halogen compounds . most industrial sites have a research and development team ; in addition the vert le petit site has the equipment required to study process safety . 14 references edit infogreffe isochem 1 isochem cherche des chemins pour grandir industrie pharma octobre 2010 . 2 isochem rach te la soci t britannique wychem industrie pharma janvier 2013 . 3 isochem renforce son offre en chimie fine et s implante en grande bretagne usine nouvelle juillet 2013 . growing challenges of api process development in custom manufacturing chimica oggi chemistry today 27 n 5 september october 2009 . hydrogenation the key specialty chemicals magazine juin 2009 . phosgene futures specialty chemicals magazine november 2011 . 4 controlled ring opening of n sulfinyl and n silyl n carboxyanhydrides nca synlett 2009 2 279 283 . amino acid n carboxyanhydrides industrial solutions for a growing demand specialty chemicals magazine 28 n 5 june 2008 . peptide synthesis and fine chemistry merging for progress pharmachem novembre december 2004 uncas focus on peptides & amino acids chimica oggi chemistry today 23 n 3 june 2005 . la soci t isochem la pointe du traitement des d chets le courrier du loiret n 3439 29 novembre 2012 isochem vise l autonomie totale traitement des rejets la r publique pithiviers 29 novembre 2012 . 5 phosgene triphosgene different approach in risk management chimica oggi chemistry today 29 n 4 july august 2011 . external links edit official website isochem official website wychem retrieved from https en.wikipedia.org w index.php title isochem company & oldid 713727735 categories chemical companies of francehidden categories articles with a promotional tone from february 2014all articles with a promotional tonearticles lacking reliable references from february 2014all articles lacking reliable referencesorphaned articles from february 2014all orphaned articlespages using infobox company with unsupported parameters navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages fran ais edit links this page was last modified on 5 april 2016 at 16 18 . text is available under the creative commons attribution sharealike license ; 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