statistical software founded 1982 headquarters minneapolis minnesota united states u.s. key people pat whitcomb founding principal and president mark anderson principal and general manager products design expert and design ease statistical software number of employees 14 website www.statease.com stat ease inc. is a privately held company producing statistical software in minneapolis minnesota founded by pat whitcomb in 1982 . the company currently has 14 employees . the company provides software packages for engineers and scientists using design of experiments methods doe for optimizing development of products and processes . it also provides doe training and consulting services . contents 1 history 2 statistical design of experiments 3 applications 4 references 5 external links history edit stat ease was founded by pat whitcomb while at general mills in 1982 . he later brought in two of his general mills colleagues tryg helseth as programmer and mark anderson as business manager . whitcomb and anderson are principals of the company today . 1 the company sold its first software in june 1985 . sales took off in 1987 when the software was described as incredibly easy to use in a review of doe software . 2 in 1988 the company released its first version of design expert software which provided the tools for response surface methods rsm for process optimization . this package complemented design ease which handled factorial designs and also provided statistical tools for optimizing mixtures in the chemical process industries . in 1996 the firm added the features of design ease into design expert version 5 and translated it from dos to windows . both packages are still marketed today . 3 in 1996 forbes magazine said the new mantra for process improvement is multivariate testing mvt and added a minneapolis software firm stat ease sells most of the software these mvt types use . 4 felix grant reviewing design expert version 7.1.3 in scientific computing magazine said in a mature well established product which dominates its market upgrades should be expected to reflect developing practice and display evolutionary growth rather than piling on attention seeking gimmicks ; and so it is here ... . core functions have been extended usefully ... the design editor in design expert dx has long been a strong point providing a central cockpit from which to intuitively refine and test most aspects but various new control features have now been added to the package small in themselves but significantly enhancing productive control . 5 statistical design of experiments edit minimum run resolution iv and minimum run resolution v experimental designs were invented by pat whitcomb and gary oehlert in 2004 . 6 minimum run resolution iv mr4 factorial designs estimate all main effects clear of two factor or higher interactions in a minimum of experimental runs . mr4 designs work well for factor screening . minimum run resolution v mr5 factorial designs estimate all main effects and two factor interactions in a minimum of experimental runs . mr5 designs are typically done after screening to a vital few factors which then need to be studied in more depth in case they interact . 7 whitcomb and oehlert won the shewell award in 2008 for invention of the half normal plot of effects for general factorials . 8 they also developed statistical tools in 2008 to calculate power for a broad range of experimental designs and precision as a power substitute via fraction of design space fds for response surface methods rsm and mixture design . 9 whitcomb and anderson have written two non academic books on doe ; the books include a free educational version of stat ease software . 10 applications edit alberto culver developed a new line of scrubs using design expert software from stat ease . 11 stat ease was used by los alamos national laboratory researchers in designing a set of experiments designed to demonstrate the application of model validation techniques to a structural dynamics problem . 12 stat ease was used by researchers to design experiments to optimize the effects of storage on the physico chemical microbiological and sensory quality on bottlegourd basil leaf juice . 13 invitrogen used stat ease design expert software to optimize a cell culture bioproduction system . the researcher states this experiment demonstrates how a robotically controlled microbioreactor system can be combined with doe methods to optimize cell culture media and feeding strategies . the new process is rich in information and provides a solid understanding of the most influential factors affecting performance of specific cell lines . 14 the united states environmental protection agency epa evaluated the physicochemical properties of nine surfactants used in the remediation of perchloroethylene pce in aqueous solutions using a response surface quadratic design model of experiment . design expert software was used to generate the experimental design and perform the analysis . the research provided predictive models for alterations in the physiochemical properties of pore fluid to surfactant enhanced acquifer remediation of pce . 15 researchers investigated the possibility of producing poly 3 hydroxybutyrate p 3hb polyester using corn syrup . the concentrations of the different ingredients were optimized using doe performed with design expert software . 16 researchers at the university of nottingham demonstrated that the dna extracted from both green and roasted beans could be used in a restriction fragment length polymorphism rflp based analysis to di erentiate between arabica and robusta types of co ee . design expert software was used for design of experiments comparing and optimizing yields using a variety of commercial dna extraction kits . 17 references edit homegrown software a trans atlantic hit chemical engineering and materials science news spring 2001 . nachtsheim tools for computer aided experiments journal of quality technology vo . 19 no. 3 july 1987 . pp 132 160 . li he design of experiments software the chemical information network july 17 2003 rita koselka the new mantra mvt forbes march 11 1996 . felix grant design expert 7.1 scientific computing world october 2007 . pat whitcomb mark anderson screening process factors in the presence of interactions american society for quality 58th annual quality congress session w202 2004 . small ef cient equireplicated resolution v fractions by gary w. oehlert and pat whitcomb october 15 2002 fall technical conference 2008 spes & qps news joint newsletter for the section on physical and engineering sciences and the quality and productivity section of the american statistical association december 2008 page 8 . pat whitcomb fds a powerful tool for designers of optimization experiments stat ease white paper september 2008 . mark anderson and pat whitcomb doe simplified practical tools for effective experimentation 2nd edition productivity press . boca raton fl 2007 and rsm simplified optimizing processes using response surface methods for design of experiments productivity press boca raton fl . jeff falk r & d test method expedites speed to market gci magazine february 2009 . scott w. doebling francois m. hemez john f. schultze validation of the transient structural response of a threaded assembly american institute of aeronautics and astronautics 43rd aiaa asme asce ahs asc structures structural dynamics and materials conference 22 25 april 2002 denver colorado t.k. majumdar d.d. wadikar c.r. vasudish k.s. premavalli and a.s. bawa effect of storage on physico chemical microbiological and sensory quality of bottlegourd basil leaves juice am . j. food technol . 6 226 234 . steve peppers doe helps optimize a cell culture bioproduction system bioprocess international vol . 7 no . s9 october 2009 pp. 24 27 . d. dale werkema jr. report on the geoelectrical detection of surfactant enhanced aquifer remediation of pce property changes in aqueous solutions due to surfactant treatment of perchloroethylene implications to geophysical measurements u.s. environmental protection agency march 2008 . ali daneshi habibollah younesi seydmahmood ghasempouri mazyar sharifzadehb production of poly 3 hydroxybutyrate by cupriavidus necator fromcorn syrup statisticalmodeling and optimization of biomass yield and volumetric productivity journal of chemical technology & biotechnology volume 85 issue 11 page 15238 1539 november 2010 . stelios spaniolas maroussa tsachaki malcolm j. bennett gregory a. tucker evaluation of dna extraction methods from green and roasted co ee beans food control volume 19 issue 3 march 2008 pages 257 262 . external links edit stat ease official website retrieved from https en.wikipedia.org w index.php title stat ease & oldid 638769811 categories software companies based in minnesotacompanies based in minnesota navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read 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