free encyclopedia jump to navigation search center for international blood & marrow transplant research cibmtr type private research firm industry research founded milwaukee wi july 1 2004 minneapolis mn july 1 2004 founder mary m. horowitz dennis l. confer mortimer m. bortin headquarters milwaukee wi and minneapolis mn u.s. 1 area served worldwide key people jeffrey chell executive director services outcomes research hematopoietic stem cell transplantation website www.cibmtr.org the center for international blood & marrow transplant research or cibmtr collaborates with the global scientific community to advance hematopoietic cell transplantation and cellular therapy research worldwide . a combined research program of the national marrow donor program and the medical college of wisconsin cibmtr facilitates critical research that has led to increased survival and an enriched quality of life for thousands of patients . contents 1 history 1.1 formation 1.2 international bone marrow transplant registry ibmtr 1.3 national marrow donor program nmdp 2 research activities 2.1 observational research 2.2 provide access to outcomes data 2.2.1 data resources 2.2.2 available resources 2.3 provide access to research repository samples 2.3.1 sample inventory 2.4 provide education guidelines and training 3 references history edit formation edit on july 1 2004 in pursuit of a mission to improve transplantation access and outcomes for patients the cibmtr was established . the new organization joined together the research programs of the national marrow donor program nmdp and the international bone marrow transplant registry ibmtr at the medical college of wisconsin . international bone marrow transplant registry ibmtr edit in 1972 just four years after the first successful hematopoietic cell transplantation hct pioneers in the field of hct realized the significance of what they were undertaking . several of the pioneers in this evolving science also understood the importance of collaborating to better understand the data being generated at individual centers . dr. mortimer m. bortin and several colleagues established the ibmtr at the medical college of wisconsin to do just that . physicians in the field agreed to voluntarily contribute their patient data to this outcomes registry . at the time there were only about 12 transplant centers and fewer than 50 patients per year worldwide receiving a transplant . national marrow donor program nmdp edit main article national marrow donor program in 1986 the u.s. navy established the national bone marrow donor registry with one full time employee housed at the st. paul mn american red cross and a sub contract with the university of minnesota for computer support and data management . the first donor search was processed in september 1987 and the first national marrow donor program nmdp facilitated transplant took place in december 1987 . again the founders knew the critical nature of collecting outcomes data and conducting collaborative research to improve outcomes requiring from that very first unrelated transplant that transplant centers report their patient outcomes to the nmdp . research activities edit observational research edit observational research is a core activity of cibmtr . investigators are invited to propose studies that utilize cibmtr s large observational database . these research studies culminate in publications in peer reviewed journals and move the field of hematopoietic cell transplantation hct toward improved outcomes and higher quality of life . since its inception in 1972 cibmtr data and statistical support have resulted in more than 700 peer reviewed publications addressing hct . studies are conducted within a working committee structure . they are guided by co chairs who are experts in the relevant field and by scientific directors who are experienced transplant physicians with ms degrees in biostatistics or related fields . ms biostatisticians coordinate working committee activities and participate in individual studies with oversight provided by phd biotatisticians . investigators from around the world are currently participating in more than 250 cibmtr studies . provide access to outcomes data edit collected data can be accessed for patient care decisions developing research studies education transplant center administrative needs and cibmtr research . data resources edit every year a variety of resources are developed from cibmtr data including publications slide sets web resources and more . investigators physicians patients and others interested in hematopoeitic cell transplantation hct outcomes can access these resources below . they collect outcomes data on every allogeneic transplantation performed in the u.s. for the sctod as required by u.s. law . u.s. transplant centers also voluntarily submit autologous transplantation data and transplant centers worldwide voluntarily submit both autologous and allogeneic transplantation data . as a result their clinical database now contains information on more than 330 000 transplant recipients . available resources edit cibmtr supports investigators in conducting hct observational studies . data available for this research includes baseline recipient data diagnosis disease sub classification or histology stage at transplant cytogenetics molecular markers pre hct disease treatment demographic socioeconomic information gender age race ethnicity transplant procedure hla typing conditioning regimen graft source mobilization t cell depletion and other graft manipulation clinical coexisting diseases pre hct infection hct history baseline donor data demographics hla typing infection disease markers pre donation cbc and differential pre donation toxicities filgrastim administration follow up recipient data collected at 100 days 6 months and annually after hct transplant outcomes survival neutrophil and platelet engraftment acute and chronic gvhd relapse gvhd prophylaxis immune reconstitution chimerism infection organ function subsequent hct or dci new malignancy cause of death follow up donor data collected at 2 days 1 week and weekly until donor reports full recovery then at 1 month 6 months and annually after donation donor outcomes post donation cbc and differential post donation toxicities adverse events product analysis cell counts viability volume provide access to research repository samples edit the nmdp research sample repository contains more than 19 000 related and unrelated paired transplant recipient donor or cord blood samples with complete validated clinical data . samples can be used for local research studies or for cibmtr research studies . sample inventory edit the national marrow donor program nmdp research sample repository contains approximately 900 000 sample aliquots from more than 19 000 related and unrelated transplant recipient donor or cord blood samples with complete validated clinical outcome data from the cibmtr observational database . the majority of the paired samples have complete high resolution data available for hla a b c drb1 3 4 5 dq and dp loci . sample types samples in the nmdp research sample repository are stored as whole blood cryo preserved whole blood plasma blood spotted on filter paper peripheral blood mononuclear cells pbmc viable and non viable b lymphoblastoid cell lines b lcl viable and non viable granulocytes serum dna whole genome amplified dna provide education guidelines and training edit cibmtr provides trends outcomes data and presentation graphics develops post transplant care guidelines and conducts meetings for education science and training . the cibmtr has published more than 500 peer reviewed papers in the medical literature since 1972 . the cibmtr reference center offers a wide range of resources for investigators physicians and patients from published studies and statistical data to guidelines for transplant patients and their families . references edit health and fitness portal hrsa.gov sctod bethematch.org nmdp official bethematchclinical.org nmdp researchers cibmtr our company . cibmtr website . retrieved august 3 2010 . retrieved from https en.wikipedia.org w index.php title center for international blood and marrow transplant research & oldid 743560373 categories organizations based in milwaukeehidden categories pages using infobox company with unsupported parameters navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 10 october 2016 at 05 45 . 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