14 35 w 40.678631 n 78.243038 w 40.678631 ; 78.243038 intercept pharmaceuticals type public company traded as nasdaq icpt industry biotechnology founded 2002 headquarters new york city new york united states key people mark pruzanski president and ceo jonathan silverstein chairman of the board of directors website www.interceptpharma.com intercept pharmaceuticals inc. is an american biopharmaceutical company incorporated in 2002 focusing on the development of novel synthetic bile acid analogs to treat chronic liver diseases such as primary biliary cirrhosis pbc non alcoholic fatty liver disease or non alcoholic steatohepatitis nash cirrhosis portal hypertension primary sclerosing cholangitis and also the intestinal disorder bile acid diarrhea . contents 1 products 2 initial public offering and stock history 3 references 4 external links products edit the company s lead product is obeticholic acid oca also known as 6 ethyl chenodeoxycholic acid or int 747 . oca is a potent first in class farnesoid x receptor fxr agonist . it is currently in phase iii studies for primary biliary cirrhosis and phase ii studies for other diseases including nash . other products in the development pipeline include int 767 a dual fxr tgr5 agonist and int 777 a tgr5 agonist . initial public offering and stock history edit intercept trades on the nasdaq exchange under the ticker symbol icpt . the initial public offering of the stock on october 16 2012 was at 15 . 1 a follow on public offering at 33 took place on june 24 2013 . on january 9 2014 the stock skyrocketed from 72.39 to 275.49 or about 280 % after a planned interim analysis by the independent data safety monitoring board showed that obeticholic acid met the main goal improvement of liver histology at the mid stage in the flint trial in nash sponsored by niddk . 2 3 the stock continued to climb to 497 over the next few days before falling back to around 317 on march 29 2014 giving a market capitalization of around 6.2 billion . in march 2014 the company released the results of the poise study of obeticholic acid in pbc which showed the drug met the trial s primary endpoint of a reduction in serum alkaline phosphatase a biomarker for the disease . 4 these results were presented at an international liver meeting in april 2014 . 5 as of 31 december 2014 the company had 136 employees . 6 references edit intercept pharmaceuticals strong biopharmaceutical ipo . seeking alpha . october 14 2012 . retrieved 2014 03 21 . the farnesoid x receptor fxr ligand obeticholic acid in nash treatment trial flint . intercept pharma . press release intercept announces nash primary endpoint met flint trial stopped early for efficacy based on highly statistically significant improvement in liver histology . retrieved january 9 2014 . intercept pharma . press release intercept announces positive pivotal phase 3 poise trial results . retrieved march 27 2014 . intercept s liver disease drug proves highly effective in study . . reuters . april 12 2014 . retrieved april 14 2014 . intercept pharmaceuticals . form 10 k annual report 2014 . retrieved october 2 2015 . external links edit intercept pharmaceuticals website . v t e pharmaceutical companies of the united states abbott laboratories acorda therapeutics actavis aderis pharmaceuticals adolor corporation alcon alexion pharmaceuticals alkermes allergan alza amgen amylin pharmaceuticals ariad pharmaceuticals aryx therapeutics avax technologies baxter international biocryst pharmaceuticals biogen biolex biovest biovista bradley pharmaceuticals bristol myers squibb cancervax century pharmaceuticals cephalon ceragenix pharmaceuticals combe incorporated cortex pharmaceuticals cotherix covance covidien cubist pharmaceuticals cutter laboratories cytosport cytrx danco laboratories dnaprint genomics epix pharmaceuticals eli lilly and company elorac endo pharmaceuticals ethicon endo surgery ethicon inc. forest laboratories galena biopharma genvec genentech genta gilead sciences hospira imclone systems institute for oneworld health intercept pharmaceuticals ista pharmaceuticals ivax corporation janssen biotech johnson & johnson kinetic concepts king pharmaceuticals kinray kv pharmaceutical leiner health products mallinckrodt martek biosciences corporation s. e. massengill company mckesson corporation mcneil laboratories melior discovery mentholatum merck & co. miles laboratories mylan myriad genetics naurex nereus pharmaceuticals northwest biotherapeutics norwich pharma services novabay pharmaceuticals nuvelo organon international ortho pharmaceutical ortho mcneil pharmaceutical osi pharmaceuticals ovation pharmaceuticals par pharmaceutical parke davis perrigo pfizer pharmaceutical product development prasco laboratories procter & gamble proteon therapeutics purdue pharma qualitest quark pharmaceuticals regeneron repros therapeutics rib x pharmaceuticals sarepta therapeutics savage laboratories schering plough g. d. searle & company sheffield pharmaceuticals smith kline & french spectrum pharmaceuticals sterling drug tanox tap pharmaceutical products tec laboratories teva pharmaceutical industries tiens biotech group titan pharmaceuticals trevena inc trubion upjohn upsher smith laboratories valeant pharmaceuticals ventria bioscience vertex pharmaceuticals verus pharmaceuticals vion pharmaceuticals inc. viropharma west pharmaceutical services wyeth zonite products corporation list of pharmaceutical companies retrieved from https en.wikipedia.org w index.php title intercept pharmaceuticals & oldid 738744037 categories companies listed on nasdaqbiotechnology companies of the united statespharmaceutical companies of the united stateshidden categories coordinates not on wikidata navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 10 september 2016 at 20 15 . text is available under the creative commons attribution sharealike license ; additional terms may apply . by using this site you agree to the terms of use and privacy policy . wikipedia is a registered trademark of the wikimedia foundation inc. a non profit organization . privacy policy about wikipedia disclaimers contact wikipedia developers cookie statement mobile view