biotechnology founded 1997 headquarters berkeley heights new jersey u.s. key people spiro rombotis ceo david p. lane founder products seliciclib cyc202 sapacitabine cyc682 aurora kinase inhibitors cyc116 net income us 19.7 million 2010 number of employees 18 2011 website http www.cyclacel.com cyclacel pharmaceuticals inc. is a biotechnology firm based in dundee scotland and short hills new jersey developing cancer drugs and treatments . cyclacel was founded in 1996 by professor david lane merlin ventures and cancer research campaign technology with the university of dundee and the university of glasgow . major shareholders include goldman sachs group tang capital management redmile group and ayer capital management . the firm is developing mechanism targeted drugs to help in the fight of cancer and other serious illness such as diabetes and hiv . contents 1 company overview 1.1 expansion 2 staff 3 see also 4 notes company overview edit cyclacel pharmaceuticals inc. is a biopharmaceutical company developing oral therapies that target the various phases of cell cycle control for the treatment of cancer and other serious diseases . professor sir david lane a recognized leader in the field of tumor suppressor biology who discovered the p53 protein founded the company in 1996 . in 1999 cyclacel pharmaceuticals was joined by professor david glover a recognized leader in the mechanism of mitosis or cell division who discovered among other cell cycle targets the mitotic kinases polo and aurora enzymes that act in the mitosis phase of the cell cycle . three product candidates are currently in clinical development . sapacitabine cyc682 a cell cycle modulating nucleoside analogue is in phase 3 development for the treatment of acute myeloid leukemia aml in the elderly under a special protocol assessment agreement with the u.s. food and drug administration and phase 2 studies for myelodysplastic syndromes lung cancer and chronic lymphocytic leukemia . seliciclib cyc202 or r roscovitine a cdk cyclin dependent kinase inhibitor is in phase 2 studies for the treatment of lung cancer and nasopharyngeal cancer and in a phase 1 trial in combination with sapacitabine . cyc116 an aurora kinase and vegfr2 inhibitor is in a phase 1 trial in patients with solid tumors . cyclacel pharmaceuticals strategy is to build a diversified biopharmaceutical business focused in hematology and oncology based on a portfolio of commercial products and a development pipeline of novel drug candidates . cyclacel pharmaceuticals align pharmaceuticals subsidiary markets directly in the u.s. xclair cream for radiation dermatitis numoisyn liquid and numoisyn lozenges for xerostomia . expansion edit after becoming the first european spin out company to raise over 100 million in private equity 1 the company had to pull out of a stock market listing in july 2004 . 2 cyclacel completed a reverse merger with xcyte therapies in december 2005 to acquire nasdaq listing . 3 this allowed cyclacel to take advantage of its adopted nasdaq listing by raising an additional 45 million in april 2006 through a private placement of stock and warrants . staff edit this section does not cite any sources . please help improve this section by adding citations to reliable sources . unsourced material may be challenged and removed . november 2007 learn how and when to remove this template message spiro rombotis president and chief executive officer . paul mcbarron executive vice president finance and chief operating officer . judy chiao vice president clinical development and regulatory affairs . gill christie director human resources . susan davis associate director business development . professor david glover frse chief scientist polgen . development . see also edit pharmaceutical industry in the united kingdom notes edit cyclacel completes 39 million private placement . bioportfolio . 2004 . archived from the original on april 16 2004 . retrieved january 29 2004 . nick bevens 2004 . cyclacel gets a 5m bail out . the scotsman . uk . retrieved october 10 2004 . xcyte sells off assets . puget sound business journal . december 15 2005 . retrieved december 15 2005 . v t e university of dundee governance chancellor the lord patel rector mark beaumont principal sir peter downes general council university court senatus academicus students representative council history medical schools mills observatory telecommunications research establishment university of st andrews academic centre for dermatology and genetic medicine centre for energy petroleum and mineral law and policy centre for gene regulation and expression division of signal transduction therapy duncan of jordanstone college of art and design medical school school of architecture school of law facilities botanic garden dundee royal infirmary formerly ninewells hospital maryfield hospital formerly perth royal infirmary student life students association shinty club east of scotland universities air squadron undergraduate gown people mary ann baxter co founder academics alumni chancellors rectors related topics caird hall canongate books cyclacel dictionary of the scots language dundee cell products dundee university press until 2013 dundee international book prize category commons v t e pharmaceutical and biotechnology industry in the united kingdom manufacturing in the united kingdom economy of the united kingdom companies current aah pharmaceuticals alliance boots astex astrazeneca medimmune btg cyclacel dechra pharmaceuticals ge healthcare genus glaxosmithkline hikma pharmaceuticals indivior macfarlan smith norbrook group oxford biomedica pfizer uk phytopharm proximagen shire silence therapeutics tbs gb unipath vectura group vernalis viiv healthcare defunct allen & hanburys amersham beecham group cambridge antibody technology celltech chiroscience distillers company fisons glaxo wellcome ici reliant pharmaceuticals renovo zeneca government and regulatory bodies commission on human medicines department of health european directorate for the quality of medicines european medicines agency medicines and healthcare products regulatory agency national collaborating centre for mental health national patient safety agency pharmaceutical price regulation scheme pharmaceutical society of northern ireland general pharmaceutical council scottish medicines consortium veterinary medicines directorate industry and professional bodies association of the british pharmaceutical industry chemical industries association european federation of biotechnology european federation of pharmaceutical industries and associations faculty of pharmaceutical medicine pharmacists defence association royal pharmaceutical society of great britain worshipful society of apothecaries books and journals bandolier bad pharma british national formulary british national formulary for children monthly index of medical specialities the pharmaceutical journal other british approved name british pharmacopoeia drugscope european and developing countries clinical trials partnership european pharmacopoeia list of world s largest pharmaceutical companies pharmaceutical services negotiating committee wellcome trust category retrieved from https en.wikipedia.org w index.php title cyclacel & oldid 738257602 categories pharmaceutical companies of scotlandcompanies based in dundee1996 establishments in scotlandpharmaceutical companies established in 1996pharmaceutical companies based in new jerseyhidden categories use mdy dates from april 2012articles needing additional references from november 2007all articles needing additional references navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what 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