industry life sciences materials science software computational chemistry cheminformatics founded 1990 founder richard a. friesner william a. goddard iii headquarters new york ny area served worldwide key people ramy farid president charles ardai chairman of the board products small molecule drug discovery suite biologics suite materials science suite discovery informatics suite pymol number of employees 250 website official page schr dinger llc is an american software company that develops chemical simulation software for use in pharmaceutical biotechnology and materials science research . the company provides products ranging from general molecular modeling programs to a full suite of chemical simulation and drug design software including ligand and structure based methods . it also provides products in various research areas including small molecule modeling and simulations macromolecular modeling and simulations lead discovery lead optimization and visualization and automation . the company s software helps scientists to accelerate their research and development activities as well as to make novel discoveries . founded in 1990 schr dinger is headquartered in new york city with operations in oregon california massachusetts germany france india the united kingdom and japan . 1 contents 1 company 2 products 3 services 4 partners 5 awards and recognition 6 references 7 external links 8 other institutions developing software for computational chemistry company edit schr dinger major offices are located new york and portland . 2 bill gates invested 10 million in 2010 through his investment company cascade under conditions that it is to be spent only for research and development . 3 gates invested another 20 million in schr dinger in december 2012 . 2 in september 2013 nimbus discovery a strategic partner of schr dinger was named one of fiercebiotech s 2013 fierce 15 in recognition of the company s novel business strategies and technology . 4 in november 2013 schr dinger in collaboration with cycle computing and the university of southern california set a record for the world s largest and fastest cloud computing run by using 156 000 cores on amazon web services to screen over 205 000 molecules for materials science research . 5 6 this work was a follow up to a collaboration in 2012 in which cycle computing created a 50 000 core virtual supercomputer using amazon infrastructure and schr dinger s glide program was used to analyze 2.1 million compounds in only 3 hours . 7 products edit schr dinger s full product offerings range from general molecular modeling programs to a comprehensive suite of drug design software as well as a suite for materials research . python apis exist for most of the software tools developed by schr dinger making it possible to build custom workflows . some of its software are canvas 8 glide 9 induced fit 10 phase 11 sitemap 12 watermap 13 14 pymol and fep . 15 16 17 services edit in addition to its software platforms schr dinger provides professional services including custom software development and training computer cluster design and implementation and research based drug discovery projects . 18 19 20 21 these professional services are provided to commercial academic and government organizations to assist with small molecule design biologics design materials science applications and implementation of enterprise level informatics . 20 22 partners edit schr dinger is a partner with nimbus discovery which uses schr dinger s drug screening and design platform in combination with a virtual globally distributed model for drug discovery . 19 20 23 24 in april 2016 nimbus announced that gilead will acquire nimbus apollo inc. a wholly owned subsidiary of nimbus therapeutics and its acetyl coa carboxylase acc inhibitor program . nimbus therapeutics will receive an upfront payment of 400 million with the potential to receive an additional 800 million in development related milestones over time . 25 26 27 28 in april 2015 sanofi signed a 120m drug discovery deal with schr dinger . 29 30 in january 2016 schr dinger announced a research collaboration with pfizer to develop a computational model for predicting key biotherapeutic properties . 31 awards and recognition edit in recognition of his contributions to original research in the field of computational chemistry schr dinger founder prof. richard a. friesner was elected to the national academy of sciences in 2016 32 and to the american academy of arts and sciences in 2008 . 33 34 in 2014 schr dinger was awarded the bioit world best practices award in the category of it infrastructure . 22 35 references edit business week company profile schr dinger . retrieved 28 august 2013 . a b schrodinger receives another 20m from bill gates . dec 2012 . retrieved 28 august 2013 . siemers erica 24 may 2010 . bill gates cash boosts drug company schrodinger llc . portland business journal . retrieved 28 august 2013 . nimbus discovery 2013 fierce 15 . retrieved 21 july 2014 . supercomputing simulation employs 156 000 amazon processor cores . nov 2013 . retrieved 21 july 2014 . the megarun . retrieved 21 july 2014 . 4 829 per hour supercomputer built on amazon cloud to fuel cancer research . apr 2012 . retrieved 21 july 2014 . duan j. ; dixon s.l. ; lowrie j.f. ; sherman w. 2010 . analysis and comparison of 2d fingerprints insights into database screening performance using eight fingerprint methods . j. molec . graph . model . 29 2 157 170 . doi 10.1016 j.jmgm .2010.05.008 . pmid 20579912 . friesner r. a. ; murphy r. b. ; repasky m. p. ; frye l. l. ; greenwood j. r. ; halgren t. a. ; sanschagrin p. c. ; mainz d. t. 2006 . extra precision glide docking and scoring incorporating a model of hydrophobic enclosure for protein ligand complexes . journal of medicinal chemistry . 49 21 6177 6196 . doi 10.1021 jm051256o . pmid 17034125 . sherman w. ; day t. ; jacobson m. p. ; friesner r. a. ; farid r. 2006 . novel procedure for modeling ligand receptor induced fit effects . journal of medicinal chemistry . 49 2 534 553 . doi 10.1021 jm050540c . pmid 16420040 . dixon s. l. ; smondyrev a. m. ; knoll e. h. ; rao s. n. ; shaw d. e. ; friesner r. a. 2006 . phase a new engine for pharmacophore perception 3d qsar model development and 3d database screening . 1 . methodology and preliminary results . j. comput . aided mol . des . 20 10 11 647 671 . doi 10.1007 s10822 006 9087 6 . pmid 17124629 . halgren t. 2009 . identifying and characterizing binding sites and assessing druggability . j. chem . inf . model . 49 2 377 389 . doi 10.1021 ci800324m . pmid 19434839 . robert abel ; tom young ; ramy farid ; bruce j. berne ; richard a. friesner 2008 . role of the active site solvent in the thermodynamics of factor xa ligand binding . j. am . chem . sco . 130 9 2817 2831 . doi 10.1021 ja0771033 . pmid 18266362 . elizabeth k. wilson 2012 . water s role in drug discovery . chem . eng . news . 90 11 64 65 . doi 10.1021 cen 09011 scitech3 . steinbrecher thomas b. ; dahlgren markus ; cappel daniel ; lin teng ; wang lingle ; krilov goran ; abel robert ; friesner richard ; sherman woody 2015 11 23 . accurate binding free energy predictions in fragment optimization . journal of chemical information and modeling . 55 11 2411 2420 . doi 10.1021 acs.jcim .5 b00538 . issn 1549 9596 . wang lingle ; deng yuqing ; knight jennifer l. ; wu yujie ; kim byungchan ; sherman woody ; shelley john c. ; lin teng ; abel robert 2013 02 12 . modeling local structural rearrangements using fep rest application to relative binding affinity predictions of cdk2 inhibitors . journal of chemical theory and computation . 9 2 1282 1293 . doi 10.1021 ct300911a . issn 1549 9618 . wang lingle ; wu yujie ; deng yuqing ; kim byungchan ; pierce levi ; krilov goran ; lupyan dmitry ; robinson shaughnessy ; dahlgren markus k. 2015 02 25 . accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free energy calculation protocol and force field . journal of the american chemical society . 137 7 2695 2703 . doi 10.1021 ja512751q . issn 0002 7863 . schr dinger and tri institutional therapeutics discovery institute announce agreement to provide drug discovery software to tri institutional researchers . sep 2013 . retrieved 20 october 2014 . a b nimbus alliances . oct 2014 . retrieved 20 october 2014 . a b c the nimbus experiment structure based drug deals . june 2013 . retrieved 20 october 2014 . schrodinger and professor mark e. thompson usc announce research collaboration to enable computer aided design of organic semiconductor materials . june 2013 . retrieved 20 october 2014 . a b bioit . july 2013 . retrieved 20 october 2014 . schr dinger s new platform for real time collaboration on drug design . april 2014 . retrieved 20 october 2014 . discovering nimbus . march 2011 . retrieved 20 october 2014 . gilead sciences announces acquisition of nimbus therapeutics acetyl coa carboxlyase acc program for nash and other liver diseases . april 2016 . retrieved 4 april 2016 . nimbus delivers its apollo mission a 1.2 b gilead partnership . april 2016 . retrieved 4 april 2016 . gilded apollo gilead takes nimbus program for potential 1.2 b . april 2016 . retrieved 4 april 2016 . gilead sciences announces acquisition of nimbus therapeutics acetyl coa carboxylase acc program for nash and other liver diseases . april 2016 . retrieved 4 april 2016 . schr dinger s new platform for real time collaboration on drug design . april 2015 . retrieved 8 april 2015 . sanofi bets on schr dinger . april 2015 . retrieved 8 april 2015 . schr dinger announces research collaboration with pfizer inc. . jan 2015 . retrieved 9 jan 2015 . national academy of sciences members and foreign associates elected american academy of arts & sciences 2008 class of fellows and foreign honorary members 2008 class of fellows and foreign honorary members the cloud s the limit rentable supercomputers for improving drug discovery . july 2011 . retrieved 20 october 2014 . external links edit schr dinger inc. web site other institutions developing software for computational chemistry edit accelrys now biovia cambridgesoft chemical computing group cresset biomolecular discovery dotmatics which licenses openeye s nomenclature tool inte ligand vlifemds software simulations plus inc. retrieved from https en.wikipedia.org w index.php title schr dinger company & oldid 732564275 categories software companies based in oregonmolecular modelling softwarecompanies based in oregontechnology companies of the united statessoftware companies established in 1990 navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools 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