nasdaq dcth is a publicly traded specialty pharmaceutical and medical device company 1 that develops percutaneous perfusion technologies for the targeted administration of high dose chemotherapeutic agents to specific organs or regions of the body . based in queensbury new york the company has an intellectual property portfolio consisting of 28 patents worldwide . delcath s percutaneous hepatic perfusion php is currently undergoing phase ii and phase iii trials against tumors in the liver . 2 delcath has a cooperative research and development agreement crada with the national cancer institute and has received fast track and a special protocol assessment from the food and drug administration for its use of melphalan in treating unresectable liver tumors . php also known as the delcath system is tested for the treatment of metastatic melanoma in the liver and for primary liver cancer and metastatic hepatic malignancies from neuroendocrine cancers and adenocarcinomas as well as patients with melanoma who previously received isolated perfusion . chemotherapy is usually delivered intravenously although a number of agents can be administered orally e.g. specialty drugs melphalan trade name alkeran busulfan capecitabine . 3 phase iii melanoma trial enrolling edit university of pittsburgh medical center national cancer institute in bethesda maryland albany medical center in albany new york john wayne cancer center in santa monica california moffitt cancer center in tampa florida morristown memorial hospital in morristown new jersey providence cancer center in portland oregon st. luke s cancer center of bethlehem pennsylvania swedish medical center in englewood colorado university of maryland medical center in baltimore maryland university of texas medical branch in galveston texas references edit melphalan granted fda orphan drug designation for treatment of cholangiocarcinoma news medical.net 20 july 2015 retrieved 6 october 2015 delcath expands phase ii multi histology clinical trial . businesswire.com . specialty pharmacy services an overview for oncology practices . the journal of hematology oncology pharmacy . 29 july 2015 . issn 2164 1161 . retrieved 6 october 2015 . external links edit delcath official website clinical trial number nct00324727 at clinicaltrials.gov metastatic melanoma in the liver clinical trial number nct00096083 at clinicaltrials.gov primary liver cancer and metastatic hepatic malignancies from neuroendocrine cancers and adenocarcinomas pingpank james f. phase i study of hepatic arterial melphalan infusion and hepatic venous hemfiltration using percutaneously placed catheters in patients with unresectable hepatic malignancies . j clin oncol 23 3456 3474 . seidel geoffrey d. part i regional chemotherapy clinical studies in nontraditional clinical settings . 10.1188 06 . cjon .338 344 . yahoo finance this oncology article is a stub . you can help wikipedia by expanding it . v t e this article about a medical pharmaceutical or biotechnological corporation or company is a stub . you can help wikipedia by expanding it . v t e retrieved from https en.wikipedia.org w index.php title delcath systems & oldid 737202821 categories companies listed on nasdaqcancer organizations based in the united stateshepatologyhealth care companies of the united statescompanies based in new york cityspecialty drugsoncology stubsmedical company stubshidden categories all stub articles navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 1 september 2016 at 09 32 . text is available under the creative commons attribution sharealike license ; additional terms may apply . by using this site you agree to the terms of use and privacy policy . wikipedia is a registered trademark of the wikimedia foundation inc. a non profit organization . privacy policy about wikipedia disclaimers contact wikipedia developers cookie statement mobile view