cite any sources . please help improve this article by adding citations to reliable sources . unsourced material may be challenged and removed . march 2015 learn how and when to remove this template message roche applied science type public nyse pki industry health sciences pharmacology biotechnology headquarters penzberg upper bavaria germany products analytical instruments genetic screening tools life & analytical science software and instruments website www.www.roche applied science.com roche applied science is a global business entity in the biotechnology sector that produces reagents and systems for life sciences research with an emphasis on molecular genetics and cell biology research needs . contents 1 scope of business 2 locations 3 history 4 instrument development 5 see also 6 references scope of business edit roche applied science produces reagents and systems for related to dna sequencing microarrays gene expression and cell analysis . important fields of application of the company s products are the research and development areas of the biotechnology and pharmaceutical industries . the company also offers reagents and systems for the pharmaceuticals and diagnostics industries . locations edit the company s headquarters is in penzberg in upper bavaria germany ; other main sites are mannheim germany rotkreuz in switzerland madison wi pleasanton ca and branford ct in the united states . history edit roche applied science was founded in 1859 as boehringer mannheim a developer of rare chemicals and pharmaceuticals . in the 1950s the bioreagents product line was developed according to the company s own needs in diagnostics research . they were the first commercially important producer of restriction enzymes they were the first supplier of klenow enzyme for sanger sequencing and they are the only supplier of a system for the non radioactive labeling of nucleic acid . instrument development edit as of 2011 roche applied science s instrumentation products included genome sequencing platforms an instrument to perform automated polymerase chain reactions pcr and product analyses and a system for real time label free cellular analysis for use in cell invasion migration studies . roche has a history of both developing new technologies and licensing them from other companies . see also edit 454 life sciences roche diagnostics references edit retrieved from https en.wikipedia.org w index.php title roche applied science & oldid 707694442 categories hoffmann la rochemultinational companies headquartered in germanypharmaceutical companies of germanyhidden categories articles lacking sources from march 2015all articles lacking sources navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 1 march 2016 at 07 20 . text is available under the creative commons attribution sharealike license ; additional terms may apply . by using this site you agree to the terms of use and privacy policy . wikipedia is a registered trademark of the wikimedia foundation inc. a non profit organization . privacy policy about wikipedia disclaimers contact wikipedia developers cookie statement mobile view