anatomy see cephalon arthropod head . cephalon inc. type subsidiary of teva pharmaceutical industries industry biotechnology biopharmaceutical founded 1987 headquarters frazer pennsylvania united states key people j. kevin buchi ceo products medical development central nervous system oncology number of employees 3 726 as of december 31 2010 website www.cephalon.com cephalon inc. was a u.s. biopharmaceutical company co founded in 1987 by frank baldino jr pharmacologist michael lewis neuroscientist and james c. kauer organic chemist all three former scientists with the dupont company . baldino served as the company s chairman and chief executive officer until his death in december 2010 . 1 the company s name comes from the adjective cephalic meaning related to the head or brain and it was established primarily to pursue treatments for neurodegenerative diseases . in the early years cephalon initially avoided involving itself in activities that would require maintaining a sales staff managing clinical trials and shepherding new drugs through the food and drug administration fda approval process . with no product to sell cephalon s only asset was its scientific expertise . that expertise proved sufficient to attract investors and the company managed to fund its operations through research grants and contracts with larger pharmaceutical firms . 2 sales revenues reached 2.8 billion in 2010 ranking cephalon among the leading biopharmaceutical companies in the world . in 2006 industry publication medad news named the company one of the ten most respected biotechnology firms in the world . cephalon employs more than 3 700 . cephalon was first included in the fortune 1000 list of u.s. companies based upon annual revenues for 2006 . on may 2 2011 teva announced its acquisition of cephalon . 3 contents 1 background 2 locations 3 management 4 legal issues 5 products 6 references 7 external links background edit the company s early research efforts were focused on the development of igf 1 an insulin like growth factor under a collaboration with chiron corporation to treat amyotrophic lateral sclerosis or lou gehrig s disease but the product has never been approved . the company developed and commercialized products for the treatment of sleep disorders pain addiction and cancer establishing the wake franchise on the basis of provigil modafinil and later nuvigil with the r enantiomer of modafinil . in addition to conducting research on kinase inhibitors and other small molecules it has licensed compounds and acquired both products and other companies including cima labs anesta and laboratoire lafon . it was from the latter company that cephalon obtained the rights to modafinil which it marketed under the trade name provigil for the treatment of excessive daytime sleepiness associated with narcolepsy sleep apnea and shift work sleep disorder . 1 sales of provigil reached nearly one billion dollars in 2008 by which time the company had acquired lafon . in february 2009 cephalon announced its intention to acquire australian biotechnology firm arana therapeutics a move that represented one of the largest changes in the australian life sciences landscape . the acquisition of arana brought cephalon its lead biologic candidate art621 for inflammatory diseases . moreover cephalon acquired biologics for the treatment of cancers . in february 2010 cephalon exercised its option to acquire ception therapeutics following receipt of positive data from a clinical study in adults with eosinophilic asthma . commenting on this frank baldino jr the ceo of cephalon said the acquisition of ception is consistent with our strategy to diversify into biologics and provides us with an important phase three asset for further development . 4 cephalon acquired chemgenex pharmaceuticals which provided cephalon with marketing rights to omapro a therapeutic agent for drug resistant cml . 5 locations edit the company was headquartered west of philadelphia in frazer pennsylvania and had research operations in nearby west chester as well as manufacturing and other operations in suburban minneapolis minnesota and salt lake city utah ; its european operations were based near paris france . management edit longtime chief financial officer j. kevin buchi succeeded baldino as ceo in 2011 . members of the board included venture capitalist william egan former cor therapeutics ceo vaughan kailian prominent healthcare economist dr. gail wilensky former smithkline beecham executive dr. martyn greenacre former harvard physician and glaxo usa head dr. charles sanders and former ambassador kevin moley . legal issues edit cephalon settled a lawsuit for 17 million in which it faced claims that baldino and other company executives had overstated the potential for a drug aimed at treating amyotrophic lateral sclerosis known informally as lou gehrig s disease . 6 the federal trade commission claimed that cephalon had made improper deals to postpone the availability of generic versions of modafinil . 1 in september 2008 cephalon paid 425 million to the federal government to settle four whistleblower lawsuits and a criminal charge alleging cephalon had marketed actiq gabitril and provigil for off label unapproved uses . 7 products edit select products that cephalon manufactures and markets include actiq fentanyl citrate cancer pain amrix cyclobenzaprine muscle relaxant fentora fentanyl cancer pain gabitril tiagabine seizures nuvigil armodafinil narcolepsy provigil modafinil narcolepsy treanda bendamustine indolent b cell non hodgkin s lymphoma nhl and chronic lymphocytic leukemia trisenox arsenic trioxide acute promyelocytic leukemia treatment references edit a b c meier barry . frank baldino jr. founder of pharmaceutical company dies at 57 the new york times december 21 2010 . retrieved december 24 2010 . history of cephalon inc. fundinguniverse . www.fundinguniverse.com . retrieved 2015 11 30 . http maya.tase.co.il bursa report.asp report cd 639962 00 & type pdf cephalon to acquire ception therapeutics . archived 1 february 2011 at webcite bennett simeon march 29 2011 cephalon agrees to acquire chemgenex potential leukemia drug key to 230m purchase delaware online bloomberg news retrieved march 30 2011 cephalon inc. company profile information business description history background information on cephalon inc. . referenceforbusiness.com . retrieved april 18 2012 . cephalon pays 425 million to settle unique off label marketing case brought by whistleblower phillips and cohen llp press release september 29 2008 . external links edit official website companies portal v t e philadelphia area corporations including the delaware valley list of companies based in the philadelphia area philadelphia based fortune 500 corporations rank in the 2015 list comcast 43 aramark 207 crown holdings 318 delaware valley based fortune 500 corporations rank in the 2015 list amerisourcebergen 16 dupont 87 lincoln national 223 universal health services 324 campbell soup 342 ugi 349 burlington stores inc. 500 other notable philadelphia based businesses amoroso s beneficial bank chemtura day & zimmermann fmc corporation independence blue cross pennsylvania real estate investment trust pep boys philadelphia media network radian group urban outfitters notable philadelphia based professional partnerships ballard spahr blank rome cozen o connor dechert drinker biddle & reath duane morris morgan lewis & bockius pepper hamilton saul ewing white and williams other notable delaware valley based businesses actua corporation airgas alliedbarton ametek aqua america asplundh bentley systems brandywine realty trust boscov s carpenter technology cephalon chemours christiana care health system crozer keystone health system david s bridal epam systems enersys hamilton lane liberty property trust penn mutual penn national gaming rita s italian ice sei investments slm sungard susquehanna international group vanguard toll brothers triumph group unisys viropharma vishay intertechnology vwr wawa wilmington trust w. l. gore and associates wsfs bank notable delaware valley based us headquarters of foreign businesses aberdeen asset management ace agustawestland astrazeneca delaware investments glaxosmithkline ing group keystone foods sap america siemens medical shire pharmaceuticals subaru teva pharmacueticals td bank notable delaware valley based division headquarters of us corporations acme cerberus capital management centocor johnson & johnson colonial penn conseco delmarva power exelon gsi commerce ebay hercules ashland mab paints sherwin williams mcneil laboratories j & j neoware hewlett packard peco exelon qvc liberty media rohm and haas dow chemical sunoco energy transfer tasty baking flowers foods v t e pharmaceutical companies of the united states abbott laboratories acorda therapeutics actavis aderis pharmaceuticals adolor corporation alcon alexion pharmaceuticals alkermes allergan alza amgen amylin pharmaceuticals ariad pharmaceuticals aryx therapeutics avax technologies baxter international biocryst pharmaceuticals biogen biolex biovest biovista bradley pharmaceuticals bristol myers squibb cancervax century pharmaceuticals cephalon ceragenix pharmaceuticals combe incorporated cortex pharmaceuticals cotherix covance covidien cubist pharmaceuticals cutter laboratories cytosport cytrx danco laboratories dnaprint genomics epix pharmaceuticals eli lilly and company elorac endo pharmaceuticals ethicon endo surgery ethicon inc. forest laboratories galena biopharma genvec genentech genta gilead sciences hospira imclone systems institute for oneworld health intercept pharmaceuticals ista pharmaceuticals ivax corporation janssen biotech johnson & johnson kinetic concepts king pharmaceuticals kinray kv pharmaceutical leiner health products mallinckrodt martek biosciences corporation s. e. massengill company mckesson corporation mcneil laboratories melior discovery mentholatum merck & co. miles laboratories mylan myriad genetics naurex nereus pharmaceuticals northwest biotherapeutics norwich pharma services novabay pharmaceuticals nuvelo organon international ortho pharmaceutical ortho mcneil pharmaceutical osi pharmaceuticals ovation pharmaceuticals par pharmaceutical parke davis perrigo pfizer pharmaceutical product development prasco laboratories procter & gamble proteon therapeutics purdue pharma qualitest quark pharmaceuticals regeneron repros therapeutics rib x pharmaceuticals sarepta therapeutics savage laboratories schering plough g. d. searle & company sheffield pharmaceuticals smith kline & french spectrum pharmaceuticals sterling drug tanox tap pharmaceutical products tec laboratories teva pharmaceutical industries tiens biotech group titan pharmaceuticals trevena inc trubion upjohn upsher smith laboratories valeant pharmaceuticals ventria bioscience vertex pharmaceuticals verus pharmaceuticals vion pharmaceuticals inc. viropharma west pharmaceutical services wyeth zonite products corporation list of pharmaceutical companies retrieved from https en.wikipedia.org w index.php title cephalon & oldid 743052068 categories pharmaceutical companies established in 1987pharmaceutical companies of the united statescompanies formerly listed on nasdaqhidden categories use mdy dates from march 2015pages using infobox company with unsupported parametersofficial website different in wikidata and wikipedia navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages catal deutschfran ais edit links this page 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