industry biotechnology headquarters carlsbad united states products mipomersen alicaforsen website www.ionispharma.com ionis pharmaceuticals nasdaq ions known as isis pharmeceuticals until december 2015 1 2 is a publicly traded pharmaceutical company based in carlsbad california united states . it has a single cholesterol reducing drug in the market and several compounds in the drug pipeline including ionis httrx the first intrathecally administered huntingtin lowering drug for huntington s disease ; 3 and nusinersen ionis smnrx an intrathecally administered antisense oligonucleotide drug for spinal muscular atrophy . the company was founded in 1989 by stanley crooke a former glaxosmithkline head of research with a view to commercialize antisense therapy . 4 references edit isis pharmaceuticals changes name to ionis pharmaceuticals . www.prnewswire.com . pr newswire ionis pharma . retrieved 22 december 2015 . fikes bradley . from isis pharma to ionis . the san diego union tribune . san diego union tribune . retrieved 22 december 2015 . landmark huntington s trial starts bbc news . bbc news . retrieved 18 april 2016 . crooke stanley t 21 july 2011 . the isis manifesto . bioentrepreneur . doi 10.1038 bioe .2011.7 . external links edit official website retrieved from https en.wikipedia.org w index.php title ionis pharmaceuticals & oldid 721215943 categories pharmaceutical companies of the united stateshuntington s diseasespinal muscular atrophyhidden categories official website different in wikidata and wikipedia navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages italiano edit links this page was last modified on 20 may 2016 at 11 40 . text is available under the creative commons attribution sharealike license ; additional terms may apply . by using this site you agree to the terms of use and privacy policy . wikipedia is a registered trademark of the wikimedia foundation inc. a non profit organization . privacy policy about wikipedia disclaimers contact wikipedia developers cookie statement mobile view