public mkea fp industry medical technology founded 2000 headquarters paris france key people sacha loiseau founder and ceo products cellvizio number of employees 120 website www.maunakeatech.com mauna kea technologies is a global medical device company focused on leading innovation in endomicroscopy the field of microscopic imaging during endoscopy procedures . the company researches develops and markets tools to visualize detect and rule out abnormalities including malignant and pre malignant tumors or lesions in the gastrointestinal and pulmonary tracts . the company s flagship product cellvizio a probe based confocal laser endomicroscopy pcle system provides physicians and researchers with real time access to histological information during standard endoscopy procedures through high resolution cellular imaging of internal tissues . cellvizio went public in july 2011 and trades on the nyse euronext exchange . contents 1 timeline 2 technology 2.1 cellvizio 3 clinical applications 3.1 barrett s esophagus 3.2 colorectal neoplasia 4 pre clinical research 5 headquarters and global presence 6 references timeline edit history 2000 founding of mauna kea technologies 2005 cellvizio pcle system receives u.s. food and drug administration fda clearance and ce mark in the european union 2008 cellvizio named runner up in the medical device category of the wall street journal s 2008 technology innovation awards 1 2010 cellvizio systems installed in over 180 hospitals and research centers worldwide 2011 launch of cellvizio 100 series ; initial public offering technology edit cellvizio edit the cellvizio system can be used during any endoscopy procedure offering a cellular level view of internal tissue . large international multi center clinical trials have demonstrated cellvizio s ability to help physicians to more accurately detect disease in real time confirm the absence of disease and make immediate treatment decisions . the cellvizio system includes miniaturized optics optical fiber bundles high speed scanning and advanced image processing components . the embedded real time image processing software combined with a high speed laser scanning unit lsu allows the cellvizo system to produce sharp images at 12 frames per second . mauna kea technologies developed a series of cellvizio confocal miniprobes designed specifically for various endoscopy procedures . the resolution of cellvizio images depends on the type of miniprobe used . the cellvizio system has received 510 k clearance from the u.s. food and drug administration fda and the european ce mark for use in the gi and pulmonary tracts . over 300 physicians and researchers at more than 200 international hospitals and research centers use the cellvizio system . over 10 000 patients have undergone endoscopy procedures where cellvizio was used . clinical applications edit through multiple clinical trials the use of pcle has been shown to be beneficial to the detection and or characterization of pre cancerous lesions . barrett s esophagus edit cellvizio provides a direct method to visualize the microstructure of the esophagus and differentiate normal versus abnormal barrett s esophagus be tissue in real time which may improve targeted sampling provide earlier disease detection and help patient management . 2 physicians have also used cellvizio imaging in conjunction with other clinically relevant parameters during be treatment procedures to guide resection or ablation to evaluate margins for residual malignancy and to visually monitor the patient s condition during follow up endoscopy procedures . 3 in many cases unnecessary procedures may be avoided which may impact on overall costs such as endoscopy suite time and pathology testing . colorectal neoplasia edit during standard colonoscopy procedures physicians remove all polyps and send them to a pathologist for analysis . pcle with cellvizio can magnify a polyp by a factor of 1 000 to help a physician detect cellular level features that differentiate cancerous from benign colorectal polyps during the colonoscopy procedure in real time . with the additional information provided by cellvizio the physician can use his her medical judgment to either leave the polyp or remove it and send it for pathological analysis or just discard it . 4 physicians also use cellvizio during follow up colonoscopies to re examine polyp resection sites to determine if re treatment is necessary . 5 mauna kea technologies hopes to expand cellvizio s use in urology surgery solid tumors pre clinical research edit mauna kea technologies also developed the cellvizio lab system for use in pre clinical research laboratories . the system s ultra thin highly flexible fibered microprobes come in a variety of sizes and tip shapes that are designed to facilitate imaging of different areas of a living animal . the cellvizo lab laser scanning unit lsu comes in three models functioning at either 488 660 nm or combined cellvizio dual band which allows it to function with a wide array of standard dyes or transgenic animals . the system s imagecell software performs the on the fly image processing that provides users with high quality high definition video sequences in real time . research applications include deep brain imaging angiogenesis peripheral nervous system visualization gi cancer research stem cells and pancreatic cancer imaging . headquarters and global presence edit european mauna kea technologies 9 rue d enghien 75010 paris france rcs 431268028 north american mauna kea technologies inc. 1325 satellite boulevard suite 108 suwanee ga 30024 usa references edit wall street journal the 2008 technology innovation awards sharma p. et al real time increased detection of neoplastic tissue in barrett s esophagus with probe based confocal laser endomicroscopy final results of a multi center prospective international randomized controlled trial . gie 2011 accepted for publication . wallace m. et al multicenter randomized controlled trial of confocal laser endomicroscopy assessment of residual neoplasia after musocal ablation or resection of gastrointestinal neoplasia in barrett s esophagus clean margin be preliminary report iccu 2011 oral presentation . buchner am shahid mw heckman mg et al. march 2010 . comparison of probe based confocal laser endomicroscopy with virtual chromoendoscopy for classification of colon polyps . gastroenterology . 138 3 834 42 . doi 10.1053 j.gastro .2009.10.053 . pmid 19909747 . http clinicaltrials.gov ct2 show nct01032044 term clean margin and pcle & rank 1 retrieved from https en.wikipedia.org w index.php title mauna kea technologies & oldid 681167562 categories medical technologycompanies based in paris navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store 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