wikipedia s notability guidelines for companies and organizations . please help to establish notability by citing reliable secondary sources that are independent of the topic and provide significant coverage of it beyond its mere trivial mention . if notability can not be established the article is likely to be merged redirected or deleted . find sources tissuemed news newspapers books scholar jstor free images december 2013 learn how and when to remove this template message tissuemed ltd. type private industry medical devices headquarters leeds west yorkshire u.k. products tissuepatch product family of surgical sealant films website www.tissuemed.com tissuemed is a medical device developer and manufacturer based in leeds uk . the company was founded in 1985 and developed the first tissue heart valve derived from pigs to receive regulatory approval ce mark in europe . this business was divested in 1999 1 and the heart values are currently sold by vascutek a terumo company under the aspire brand . 2 3 thereafter tissuemed focused on the development of innovative tissue adhesives for internal surgical use including a light activated tissue sealant to prevent blood loss during vascular anastomosis the tissuebond system . 4 5 more recently in 2007 tissuemed launched tissuepatch a range of surgical sealant films for the prevention of leaks during surgery including thoracic general and neurosurgery . 6 7 these products incorporate a unique synthetic bioadhesive that forms a covalent bond with tissue proteins enabling adhesion to internal organs and achieving a sealing effect . references edit aortech buys tissuemed s heart valve division . elservier business intelligence 1999 . http www.elsevierbi.com deals 199910268 kumar p ; athanasiou t ; mussa s ; wood aj . 2003 . ten year experience with aspire tissuemed porcine bioprosthesis single centre experience . . cardiovascular surgery . 11 2 131 7 . doi 10.1016 s0967 2109 03 00011 5 . pmid 12664048 . goldsmith ir ; spyt tj ; boehm m ; kendall s ; rosin md. 2001 . midterm evaluation of the tissuemed aspire porcine bioprosthesis 493 patients 506 bioprostheses . . the annals of thoracic surgery . 71 5 1471 6 . doi 10.1016 s0003 4975 01 02397 9 . pmid 11383785 . birch jf ; mandley dj ; williams sl ; worrall dr ; trotter pj ; wilkinson f ; bell pr . 2000 . methylene blue based protein solder for vascular anastomoses an in vitro burst pressure study . . lasers in surgery and medicine . 26 3 323 9 . doi 10.1002 sici 1096 9101 2000 26 3 323 aid lsm11 3.0 . co ; 2 r. us patent 6 239 190 enhancement of activation for biological tissue adhesives bonding agents and sealants using color change chromophores published 2001 assigned to tissuemed ltd ferroli p ; acerbi f ; broggi m ; schiariti m ; albanese e ; tringali g ; franzini a ; broggi g mar apr 2013 . a novel impermeable adhesive membrane to reinforce dural closure a preliminary retrospective study on 119 consecutive high risk patients . . world neurosurgery . 79 3 4 551 7 . doi 10.1016 j.wneu .2011.09.022 . pmid 22120260 . schiariti m acerbi f broggi m tringali g raggi a broggi g ferroli p. two alternative dural sealing techniques in posterior fossa surgery polylactide co glycolide self adhesive resorbable membrane versus polyethylene glycol hydrogel . surg neurol int . 2014 dec 3 ; 5 171 . doi 10.4103 2152 7806.146154 . retrieved from https en.wikipedia.org w index.php title tissuemed & oldid 689183933 categories medical deviceshidden categories articles with topics of unclear notability from december 2013all articles with topics of unclear notabilityuse mdy dates from december 2013 navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 5 november 2015 at 13 22 . text is available under the creative commons attribution sharealike license ; additional terms may apply . by using this site you agree to the terms of use and privacy policy . wikipedia is a registered trademark of the wikimedia foundation inc. a non profit organization . privacy policy about wikipedia disclaimers contact wikipedia developers cookie statement mobile view