as nasdaq aria industry pharmaceuticals biotechnology founded 1991 headquarters cambridge ma united states key people paris panayiotopoulos ceo since december 2016 alex denner chairman of the board harvey berger retired as of december 2015 chairman & ceo timothy p. clackson president of research and development and chief scientific officer products ridaforolimus under development ponatinib fda approved trade name iclusig brigatinib under development revenue us 178.98 m fy 2010 1 operating income us 104.90 m fy 2010 1 net income us 85.25 m fy 2010 1 total assets us 50.4 m fy 2010 2 number of employees 125 2011 slogan leading the pathway to better cancer therapies website www.ariad.com ariad pharmaceuticals inc. is an oncology company founded in 1991 and headquartered in cambridge massachusetts . on december 14 2012 the fda approved ariad pharmaceutical s leukemia drug iclusig for patients with all forms of chronic myeloid leukemia or philadelphia chromosome positive acute lymphoblastic leukemia who are resistant or unable to tolerate other tyrosine kinase therapies on the market . the drug was temporarily withdrawn from the market in november 2013 3 because of the risk of life threatening blood clots and severe narrowing of blood vessels . 4 this suspension was partially lifted on dec. 20 2013 with ponatinib being issued revised prescribing information a new black box warning and a risk evaluation and mitigation strategy in place to better evaluate the risks and benefits of using the drug . ariad also has brigatinib a lung cancer drug which has completed its registration trial in alk fusion driven non small cell lung cancer as of june 2016 . contents 1 company history 2 products 2.1 fda approved products 2.2 products under development 3 see also 4 references 5 external links company history edit ariad is engaged in the discovery development and commercialization of medicines for cancer patients . it offers iclusig ponatinib a tyrosine kinase inhibitor for the treatment of adult patients with chronic myeloid leukemia cml and philadelphia chromosome positive acute lymphoblastic leukemia in the united states and europe . various investigator sponsored trials are ongoing in several indications including first line and second line cml acute lymphoblastic leukemia bcr abl acute myeloid leukemia flt3 inhibitor non small cell lung cancer ret fgfr advanced biliary cancer with fgfr2 fusions and other cancers with activating mutations involving the following genes fgfr1 fgfr2 fgfr3 fgfr4 ret and kit . 5 in addition its product pipeline consists of brigatinib an investigational inhibitor of anaplastic lymphoma kinase for treating advanced solid tumors comprising non small cell lung cancer . this drug reported results of its registration trial at asco june 6 2016 with encouraging results ; 6 ap32788 an inhibitor of solid tumors with egfr and her2 activating mutation which began phase i testing in the second quarter of 2016 ; 7 and ridaforolimus an investigational mtor inhibitor for various types of cancers . the company sells and markets iclusig through specialty pharmacies and specialty distributors in the united states . it has collaboration and license agreement with medinol ltd. and icon medical corp. to develop and commercialize stents and other medical devices to deliver ridaforolimus . on february 21 2014 ariad pharmaceuticals announced the appointment of sarissa capital s alexander j. denner ph.d. to a two year term on the company s board of directors . previously dr. denner served as a senior managing director at carl icahn s icahn capital and is currently ariad s second largest shareholder . on january 10 2016 ariad announced that denner had become the chairman of the board replacing harvey berger . 8 shortly thereafter the company announced the termination of its shareholder s rights plan the poison pill . 9 in july 2015 the company announced it was due to receive up to 200 million through a royalty financing deal with pdl biopharma on future sales of ponatinib . 10 products edit fda approved products edit ponatinib iclusig products under development edit ridaforolimus formerly deforolimus partnered with merck brigatinib formerly ap26113 see also edit companies portal merck bristol myers squibb pfizer references edit a b c aria annual income statement ariad pharmaceuticals inc. annual financials . marketwatch.com . ariad reports first quarter 2010 financial results and development progress . reuters . https medicalletter.wordpress.com 2013 11 21 ponatinib withdrawn a pharmaceutical tragedy http www.fda.gov drugs drugsafety ucm373040.htm https clinicaltrials.gov ct2 results term ponatinib & search search http phx.corporate ir.net external.file item ugfyzw50suq9mzqxmdk4fenoawxksuq9ltf8vhlwzt0z & t 1 & cb 636008135469722045 http www.ariad.com research development ap32788 http www.businesswire.com news home 20160110005030 en ariad announces election alex denner chairman board http www.businesswire.com news home 20160111005320 en ariad announces termination shareholder rights plan http www.genengnews.com gen news highlights ariad to receive up to 200m in royalty deal 81251568 external links edit official ariad site v t e pharmaceutical companies of the united states abbott laboratories acorda therapeutics actavis aderis pharmaceuticals adolor corporation alcon alexion pharmaceuticals alkermes allergan alza amgen amylin pharmaceuticals ariad pharmaceuticals aryx therapeutics avax technologies baxter international biocryst pharmaceuticals biogen biolex biovest biovista bradley pharmaceuticals bristol myers squibb cancervax century pharmaceuticals cephalon ceragenix pharmaceuticals combe incorporated cortex pharmaceuticals cotherix covance covidien cubist pharmaceuticals cutter laboratories cytosport cytrx danco laboratories dnaprint genomics epix pharmaceuticals eli lilly and company elorac endo pharmaceuticals ethicon endo surgery ethicon inc. forest laboratories galena biopharma genvec genentech genta gilead sciences hospira imclone systems institute for oneworld health intercept pharmaceuticals ista pharmaceuticals ivax corporation janssen biotech johnson & johnson kinetic concepts king pharmaceuticals kinray kv pharmaceutical leiner health products mallinckrodt martek biosciences corporation s. e. massengill company mckesson corporation mcneil laboratories melior discovery mentholatum merck & co. miles laboratories mylan myriad genetics naurex nereus pharmaceuticals northwest biotherapeutics norwich pharma services novabay pharmaceuticals nuvelo organon international ortho pharmaceutical ortho mcneil pharmaceutical osi pharmaceuticals ovation pharmaceuticals par pharmaceutical parke davis perrigo pfizer pharmaceutical product development prasco laboratories procter & gamble proteon therapeutics purdue pharma qualitest quark pharmaceuticals regeneron repros therapeutics rib x pharmaceuticals sarepta therapeutics savage laboratories schering plough g. d. searle & company sheffield pharmaceuticals smith kline & french spectrum pharmaceuticals sterling drug tanox tap pharmaceutical products tec laboratories teva pharmaceutical industries tiens biotech group titan pharmaceuticals trevena inc trubion upjohn upsher smith laboratories valeant pharmaceuticals ventria bioscience vertex pharmaceuticals verus pharmaceuticals vion pharmaceuticals inc. viropharma west pharmaceutical services wyeth zonite products corporation list of pharmaceutical companies retrieved from https en.wikipedia.org w index.php title ariad pharmaceuticals & oldid 724270338 categories companies listed on nasdaqmerckpharmaceutical companies of the united statespharmaceutical companies established in 1991companies based in cambridge massachusettsbiotechnology companies of the united statescompanies in the nasdaq biotechnology index1991 establishments in massachusettslife sciences industry navigation menu personal tools not logged intalkcontributionscreate 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