pharmaceuticals health care founded 1979 headquarters horsham pennsylvania u.s. key people michael yang immunology president products golimumab iv simponi aria infliximab remicade golimumab simponi ustekinumab stelara parent johnson & johnson website www.janssenbiotech.com janssen biotech inc. formerly centocor biotech inc. is a biotechnology company that was founded in philadelphia in 1979 with an initial goal of developing new diagnostic assays using monoclonal antibody technology . contents 1 history 2 products 3 references 4 external links history edit in 1982 centocor transitioned into a publicly traded company . subsequently the company moved to a larger facility in malvern pennsylvania a northwest suburb of philadelphia . in 1984 centocor opened an overseas plant in leiden the netherlands . in 1997 eighteen years after its foundation centocor achieved its first year of operating profitability . citation needed in 1998 centocor sold its diagnostic division to fujirebio inc. . 1 in 1999 centocor became a wholly owned subsidiary of johnson & johnson the worldwide manufacturer and marketer of healthcare products . since being acquired by johnson and johnson centocor has increased its annual sales from approximately 500 million to more than 2 billion . during the same period research and development investment increased from 75 million to more than 300 million . citation needed in 2004 centocor purchased a new manufacturing plant in st. louis missouri and is currently opening a new manufacturing facility in county cork ireland . the dutch plant has been expanded substantially with a 250 million investment in additional production facilities which were opened in 2006 . citation needed in 2007 centocor broke new ground in advertising by releasing innerstate believed to be the first theatrically released documentary film both created and entirely funded by a drug company to promote remicade infliximab . 2 in 2008 centocor inc. and ortho biotech inc. merged to form centocor ortho biotech inc. in june 2010 centocor ortho biotech acquired respivert a privately held drug discovery company focused on developing small molecule inhaled therapies for the treatment of pulmonary diseases . 3 in june 2011 centocor ortho biotech changed its name to janssen biotech inc. as part of a global effort to unite the janssen pharmaceutical companies around the world under a common identity . in december 2014 the company announced it would co develop macrogenics cancer drug candidate mgd011 which targets both cd19 and cd3 proteins in treating b cell malignant tumours . this could net macrogenics up to 700 million . 4 in january 2015 the company announced it will utilise isis pharmaceuticals rna targeting technology to discover and develop antisense drugs targeting autoimmune disorders of the gastrointestinal tract with the partnership potentially generating up to 835 million for isis . 5 products edit in 1984 centocor developed their first product approved by the u.s. food and drug administration fda a diagnostic test used to detect the rabies virus . citation needed in 1998 the company launched its top selling monoclonal antibody remicade infliximab for its first fda approved indication in crohn s disease . subsequently remicade s market has expanded with approvals for rheumatoid arthritis ankylosing spondylitis psoriatic arthritis ulcerative colitis and pediatric crohn s disease . remicade was approved for plaque psoriasis in september 2006 . centocor also markets reopro abciximab a biologic agent indicated as an adjunct to coronary angioplasty ptca . in 2009 the u.s. fda approved simponi a human monoclonal antibody for treatment for arthritis which was co developed with medarex inc. 6 references edit centocor reaches agreement to sell oncology diagnostics business 1998 press release stephanie saul . drug gets a cameo in a film backed by its maker new york times february 21 2007 . http www.nytimes.com 2007 02 21 business media 21adco.html centocor ortho biotech acquires respivert news article from infogrok . http www.genengnews.com gen news highlights janssen joins macrogenics in up to 700m cancer collaboration 81250728 http www.genengnews.com gen news highlights janssen isis pharma ink up to 835m antisense agreement 81250763 marcial gene 4 may 2009 . marcial medarex a bright spot in biotech . businessweek.com . retrieved 24 sep 2014 . external links edit us site dutch site v t e johnson & johnson ceos and presidents current alex gorsky chairman and ceo robert wood johnson i james wood johnson robert wood johnson ii robert wood johnson iii philip b. hofmann richard b. sellars james e. burke ralph s. larsen selected subsidiaries alza corporation cilag crucell depuy inc. ethicon endo surgery inc. ethicon inc. independence technology llc j & j prd janssen biotech janssen pharmaceutica lifescan mcneil consumer & specialty pharmaceuticals mcneil nutritionals ortho mcneil pharmaceutical ortho neutrogena penaten tibotec major brands acuvue aveeno band aid benadryl benecol us license caladryl clean & clear desitin imodium johnson s baby lactaid listerine motrin mylanta mylicon neosporin neutrogena onetouch pepcid plax rembrandt splenda sudafed tylenol visine annual revenue us 74.3 billion fy 2014 annual net income us 16.3 billion fy 2014 employees 118 700 v t e pharmaceutical companies of the united states abbott laboratories acorda therapeutics actavis aderis pharmaceuticals adolor corporation alcon alexion pharmaceuticals alkermes allergan alza amgen amylin pharmaceuticals ariad pharmaceuticals aryx therapeutics avax technologies baxter international biocryst pharmaceuticals biogen biolex biovest biovista bradley pharmaceuticals bristol myers squibb cancervax century pharmaceuticals cephalon ceragenix pharmaceuticals combe incorporated cortex pharmaceuticals cotherix covance covidien cubist pharmaceuticals cutter laboratories cytosport cytrx danco laboratories dnaprint genomics epix pharmaceuticals eli lilly and company elorac endo pharmaceuticals ethicon endo surgery ethicon inc. forest laboratories galena biopharma genvec genentech genta gilead sciences hospira imclone systems institute for oneworld health intercept pharmaceuticals ista pharmaceuticals ivax corporation janssen biotech johnson & johnson kinetic concepts king pharmaceuticals kinray kv pharmaceutical leiner health products mallinckrodt martek biosciences corporation s. e. massengill company mckesson corporation mcneil laboratories melior discovery mentholatum merck & co. miles laboratories mylan myriad genetics naurex nereus pharmaceuticals northwest biotherapeutics norwich pharma services novabay pharmaceuticals nuvelo organon international ortho pharmaceutical ortho mcneil pharmaceutical osi pharmaceuticals ovation pharmaceuticals par pharmaceutical parke davis perrigo pfizer pharmaceutical product development prasco laboratories procter & gamble proteon therapeutics purdue pharma qualitest quark pharmaceuticals regeneron repros therapeutics rib x pharmaceuticals sarepta therapeutics savage laboratories schering plough g. d. searle & company sheffield pharmaceuticals smith kline & french spectrum pharmaceuticals sterling drug tanox tap pharmaceutical products tec laboratories teva pharmaceutical industries tiens biotech group titan pharmaceuticals trevena inc trubion upjohn upsher smith laboratories valeant pharmaceuticals ventria bioscience vertex pharmaceuticals verus pharmaceuticals vion pharmaceuticals inc. viropharma west pharmaceutical services wyeth zonite products corporation list of pharmaceutical companies retrieved from https en.wikipedia.org w index.php title janssen biotech & oldid 688809559 categories janssen biotechjanssen pharmaceuticajohnson & johnsonbiotechnology companies of the united statespharmaceutical companies of the united stateshidden categories all articles with unsourced statementsarticles with unsourced statements from september 2014 navigation menu personal tools 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