founder dr. gerry shaw headquarters gainesville florida united states area served worldwide key people dr. gerry shaw products antibodies to neural and yeast proteins website homepage of encor encor biotechnology is a united states company that manufactures antibodies to neural and yeast proteins . founded in 1999 as a spin off from the university of florida by dr. gerry shaw a british scientist and professor at the university of florida the company is based in gainesville florida and markets antibody reagents originally made for research purposes but which also have commercial value . contents 1 history 2 publications 3 references 4 external links history edit encor biotechnology was formed in at the end of 1999 to market antibody reagents originally made for research purposes but which also had some commercial potential . 1 three years later encor moved into rented lab space at the sid martin biotechnology incubator a facility dedicated to commercialization of intellectual property generated in the university of florida . the company quickly become profitable and in 2006 relocated to new premises in gainesville . 2 rat brain cells grown in tissue culture and stained in green with an antibody to neurofilament subunit nf l hgnc name nefl which reveals a large neuron . the encor biotechnology antibodies culture in the above image was stained in red for alpha internexin which in this culture is found in neuronal stem cells . in 2005 encor began collaborating with basic scientists and clinicians to produce articles in peer reviewed scientific publications focused on the examination of various plasma serum and csf biomarkers of nervous system damage and degeneration . one of these is the phosphorylated axonal form of the major neurofilament protein heavy chain protein which has the hgnc name nefh 3 4 5 6 though is usually referred to as pnf h in the scientific literature . two further studies describe novel encor assays for uchl1 7 and alpha synuclein 8 two major brain proteins implicated in the development of parkinson s and other neurological diseases . by 2012 encor product line had increased to almost 100 products the antibodies mostly being used for research purposes with a particular focus on immunocytochemistry and western blotting though many are also utilized for immunoprecipitation and elisa . some have become useful for diagnostic histopathology and for monitoring the levels of protein biomarkers of research and potential clinical utility . encor supplies reagents to research labs and other reagent companies such as abcam covance invitrogen millipore corporation and novus biologicals . publications edit shaw g yang c ellis r anderson k parker mickle j scheff s pike b anderson dk howland dr nov 2005 . hyperphosphorylated neurofilament nf h is a serum biomarker of axonal injury . biochem . biophys . res . comm . 336 4 1268 1277 . doi 10.1016 j.bbrc .2005.08.252 . pmid 16176808 . references edit biotech venture gainesville.com . gainesville.com . 2012 . retrieved 2 may 2012 . uf professor s biotech firm graduates gainesville.com . gainesville.com . 2012 . retrieved 2 may 2012 . shaw g yang c ellis r anderson k parker mickle j scheff s pike b anderson dk howland dr nov 2005 . hyperphosphorylated neurofilament nf h is a serum biomarker of axonal injury . biochem . biophys . res . comm . 336 4 1268 1277 . doi 10.1016 j.bbrc .2005.08.252 . pmid 16176808 . anderson kj scheff sw miller km roberts kn gilmer lk yang c shaw g sep 2008 . the phosphorylated axonal form of the neurofilament subunit nf h pnf h as a blood biomarker of traumatic brain injury . j. neurotrauma . 25 9 1079 1085 . doi 10.1089 neu .2007.0488 . pmc 2820728 . pmid 18729720 . gresle mm shaw g jarrott b alexandrou en friedhuber a kilpatrick tj butzkueven h dec 2008 . validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis . j. neurosci . res . 86 16 3548 3555 . doi 10.1002 jnr .21803 . pmid 18709652 . boylan k yang c crook j overstreet k heckman m wang y borchelt d shaw g dec 2009 . immunoreactivity of the phosphorylated axonal neurofilament h subunit pnf h in blood of als model rodents and als patients evaluation of blood pnf h as a potential als biomarker . j. neurochem . 111 5 1182 1191 . doi 10.1111 j. 1471 4159.2009.06386.x . pmid 19765193 . lewis sb wolper r chi yy miralia l wang y yang c shaw g may 2010 . identification and preliminary characterization of ubiquitin c terminal hydrolase 1 uchl1 as a biomarker of neuronal loss in aneurysmal subarachnoid hemorrhage . . j. neurosci . res . 88 7 1475 1484 . doi 10.1002 jnr .22323 . pmid 20077430 . tinsley rb kotschet k modesto d ng h wang y nagley p shaw g horne mk sep 2010 . sensitive and specific detection of synuclein in human plasma . . j. neurosci . res . 88 12 2693 2700 . doi 10.1002 jnr .22417 . pmid 20648655 . article about university of florida start up companies from business week 2007 gainesville sun article about one of encor s discoveries 2005 external links edit official website retrieved from https en.wikipedia.org w index.php title encor biotechnology & oldid 722757931 categories biotechnology companies of the united statescompanies based in gainesville floridatechnology companies established in 1999research support companies navigation menu personal tools not logged intalkcontributionscreate accountlog in namespaces article talk variants views read edit view history more search navigation main pagecontentsfeatured contentcurrent eventsrandom articledonate to wikipediawikipedia store interaction helpabout wikipediacommunity portalrecent changescontact page tools what links hererelated changesupload filespecial pagespermanent linkpage informationwikidata itemcite this page print export create a bookdownload as pdfprintable version languages add links this page was last modified on 30 may 2016 at 00 15 . text is available under the creative commons attribution sharealike license ; additional 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