of miniaturized sustained release drug delivery products and is continuing the evolution of these systems . our lead development product iluvien is licensed to alimera sciences inc. and utilizes the third generation of the durasert technology . the us food and drug administration fda approved iluvien for the treatment of diabetic macular edema dme for patients treated with a course of corticosteroids and did not have a significant rise in intraocular pressure iop . our proven proprietary technologies enable us to achieve highly focused long term delivery of therapeutics . we have developed three of the only four products approved by either the us or eu for the long term sustained released delivery of drug to treat chronic eye disease . additionally iluvien for diabetic macular edema dme has received marketing authorization in 17 eu countries . these marketing authorizations followed a positive outcome of the european decentralized procedure involving these countries . iluvien is commercially available in the uk germany and portugal . iluvien licensed to alimera sciences inc. alimera is approved for use in the treatment of vision impairment associated with chronic dme considered insufficiently responsive to available therapies . iluvien is a tiny device that provides sustained release of the drug fluocinolone acetonide for approximately 3 years . by injecting it directly into the back of the eye the drug is released in its site of action eliminating risks of systemic exposure . iluvien uses a third generation of durasert our miniature sustained release drug delivery technology . in addition to the application of this product in dme licensed to alimera psivida is independently developing the product for the treatment of posterior uveitis . the fda recently cleared the company s investigational new drug ind application to treat posterior uveitis with our injectable sustained release micro insert permitting psivida to move directly to two phase iii trials under which we would enroll a total of 300 patients . the fda is allowing psivida to reference much of the data including the clinical safety data from the clinical trials of iluvien for dme previously conducted by alimera . under the terms of our collaboration agreement with alimera psivida has joint ownership of and reference rights to all clinical data and regulatory filings generated by alimera including its new drug application nda for dme . psivida s other two fda approved sustained release products to treat chronic back of the eye diseases are retisert for the treatment of posterior uveitis and vitrasert for the treatment of aids related cytomegalovirus cmv retinitis . psivida has licensed both of these products to bausch & lomb incorporated . vitrasert and retisert provide sustained release for six to nine months and two and a half years respectively . psivida has a worldwide collaborative research and license agreement with pfizer inc. to develop a long term sustained release implant to deliver latanoprost for patients with ocular hypertension and glaucoma . this collaboration is focused on developing a bioerodible version of psivida s proprietary durasert technology designed to be injected into the subconjunctival space of the eye . psivida is developing a series of additional miniaturized bioerodible sustained release systems to deliver a range of proteins and small drug molecules to virtually any site in the body . one of these systems is tethadur a nanostructured bioerodible material . psivida s intellectual property portfolio consists of over 150 issued patents in countries including the u.s. europe japan china and australia . psivida a nasdaq listed company psdv is developing products designed to revolutionize treatments with a primary focus in ophthalmology . tel 617 926 5000 fax 617 926 5050 us web site terms and conditions info psivida.com about products & technology news & events investors patient advocacy careers about products & technology news & events investors patient advocacy careers sitemap contact