shower stalls & bases
orphan g protein coupled receptors and novel neuropeptides
over the last decade it has been shown that orphan g protein coupled receptors gpcrs can be used as targets to discover novel neuropeptides . a dozen neuropeptides have been identified through this approach . each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses . for example the orexins mch and ghrelin carry fundamental roles in regulating food intake while neuropeptide s neuromedin s the prokineticins and the orexins are major players in modulating sleep and circadian rhythms . the chapters of this book review the latest research in the field most of them are written by the original discoverers of the respective novel neuropeptide . emphasis is set not only on their discovery but also on their functional significance . since many of these neuropeptides are part of drug discovery programs this book impacts academic as well as pharmaceutical research . written for neurobiologists endocrinologists pharmaceutical companies