Drug Metabolism: Databases and High-Throughput Testing During Drug Development

Overview

Given the proliferation of technical data, and our increasing ability to rapidly disseminate it using electronic networks, it is no wonder that systems to manage and integrate this data are regarded as essential emerging technologies. The primary focus of this volume is one such area of data management; metabolism databases and their use in the development of new drugs.

Edited by internationally renowned scientist, P W Erhardt of the University of Toledo, this volume balances a thorough review of past case studies of drug metabolism data, with an examination of current trends in this area of data management and emerging products in this field. A mix of academic and industrial participants contributed to the book's three main sections along with vendors of key commercial products in this area.

This volume, the product of one and a half years work by the Working Party established by the International Union of Pure and Applied Chemistry, illustrates how metabolism databases may be able to be constructed and manipulated so as to partner with enhanced-throughput methodologies in a truly synergistic manner.

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