Statistical Genomics References

Books

• NTJ Bailey (1961) Introduction to the Mathematical Theory of Genetic Linkage. Clarendon Press, Oxford.
• MG Bulmer (1985) The Mathematical Theory of Quantitative Genetics. Clarendon Press, Oxford.
• M Lynch and B Walsh (1997) Fundamentals of Quantitative Genetics. Sinauer Associates.
• J Ott (1991) Analysis of Human Genetic Linkage (rev). John Hopkins U Press.
• B Weir (1997) Genetic Data Analysis, 2nd. ed. Sinauer Associates.

Journal Articles & Software by Section

1. Genetic Linkage & Linkage Maps
2. Likelihood-Based Methodology
3. Complex Traits, QTLs & Polygenes
4. Data Resampling & Simulation
5. Combining Data Across Experiments

• Other Linkage Information
• ``Statistical Problems in Genetics and Molecular Biology'', Statistical Science 9: 307-381.

Genetic Linkage & Linkage Maps

• Lander and Green (1987) ``Construction of multilocus genetic linkage maps in humans'' PNAS 84: 2363-2367.
• NE Morton (1995) ``LODs past and present'', Genetics 140: 7-12.

  Likelihood-Based Methodology

  Complex Traits, QTLs & Polygenes

• CJ Basten, BS Weir and Z-B Zeng (1995) ``A tutorial and reference manual for QTL Cartographer'', Center for Quantitative Genetics, NC St U.
• Jansen and Stam (1994) ``High resolution of quantitative traits into multiple loci via interval mapping'', Genetics 140: 1111-1127.
• C Haley and S Knott (1992) ``A simple regression method for mapping quantitative trait loci of linked factors'', J Genetics 8: 299-309.
• C Haley, S Knott and Elsen (1994) ``Mapping quantitative trait loci in crosses between outbred lines using least squares'', Genetics 136: 1195-1207.
• Lander and Botstein (1989) ``Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps'', Genetics 121: 185-199.
• Z-B Zeng (1993) ``Theoretical basis of separation of multiple linked gene effects on mapping quantitative trait loci'', PNAS USA 90: 10972-10976.
• Z-B Zeng (1994) ``Precision mapping of quantitative trait loci'', Genetics 136: 1457-1468.

  Data Resampling & Simulation

• GA Churchill and RW Doerge (1994) ``Empirical threshold values for quantitative trait mapping'', Genetics 138: 963-971.
• Jansen (1993)
• L Kruglyak and ES Lander (1995) ``A nonparametric approach for mapping quantitative trait loci'', Genetics 139: 1421-1428.
• JM Satagopan, BS Yandell, M Newton and TC Osborn (1995) ``Markov chain Monte Carlo approach to detect polygene loci for complex traits'', UW-Madison Statistics Department TR 925r, 1995. (abstract)

  Combining Data Across Experiments

• C Jiang and Z-B Zeng (1995) ``Multiple trait analysis of genetic mapping for quantitative trait loci'', Genetics 140: 1111-1127.