Detecting Patterns in Gene Expression Microarray Data:
A Microarray Study for Ways of Knowing Biology
A gene expression microarray consists of thousands of genes on a tiny
"chip" that can measure expression levels (that is, mRNA activity) in
living tissue. They are being used more and more to characterize
differential response to environmental, physiological and developmental
conditions. I am working with a biochemistry lab to study the genetic
basis of diabetes and obesity. We will examine how one might design an
experiment to uncover important obesity and diabetes genes, and then
explore data from one or more studies. This research will be a "dry
lab": we use computer graphics to analyze data and summarize what we
find.
This page is being designed for the Ways of Knowing Biology
course. Class is scheduled for Monday, 2 April, 2001, 1321
CompSci&Stat Center, 3-5pm.
References on microarrays can be found on the Reference Page. I will pull out some specific to
class needs closer to the time.
Return to Statistical Genomics Course Page.
www.stat.wisc.edu/~yandell/statgen/course/
by Brian Yandell
(yandell@stat.wisc.edu)