This talk was originally given in 2002 at the
American Society for Biochemistry & Molecular Biology,
New Orleans, LA;

It has been given in similar form at
Biochem 711 Sequence Analysis guest lecture,
Department of Biochemistry, UW-Madison,
and at
Computational Approaches to Analyzing Gene Expression Data,
BioPharmaceutical Technology Center Institute (www.btci.org),
Fitchburg, WI.